I needed to do a small .Net application that could tweet but more importantly send private messages via twitter. Twitterizer makes this extremely easy, if you can get it to work.
I found the following link:
Twitterizer 2 and C# – Namespace could not be found
This explains how to get it to work in VS 2010 in c#, at the bottom I’ve added how to get it to work in vb.net.